Mesenchymal Stem Cells Knee Osteoarthritis

Mesenchymal stem cells which come from your bone marrow can grow into.

Mesenchymal stem cells knee osteoarthritis.

We investigated the safety and efficacy of intra articular injection of placental mesenchymal stem cells mscs in knee oa healing. Knee osteoarthritis oa is a common skeletal impairment that can cause many limitations in normal life activities. Preliminary report of four patients preliminary report of four patients int j rheum dis 142 2011 pp. Mesenchymal stromal cells however are immune privileged7 or immune evasive8 and inhibit.

Osteoarthritis is a degenerative joint disease characterized by the destruction of joint cartilage. Allogeneic cells would be cheaperand logistically moreconvenient themostobvious disadvantage of using these cells is the possibility of host immune rejection. However cell expansion makes the procedure slow and expensive. Numerous systematic reviews investigating the effects of mesenchymal stem cells mscs in treating knee osteoarthritis oa have been published with controversial conclusion.

Stem cells are considered to be one of the greatest potential treatments to cure degenerative diseases. Nikbinmesenchymal stem cell therapy for knee osteoarthritis. Many patients with osteoarthritis of the knee fail non operative measures and elect to have knee arthroplasty to improve their quality of life. This perspective will discuss progress being made with the use of mesenchymal stem cells for the treatment of osteoarthritis oa with particular reference to current studies and the published literature to assess the potential of this emerging area of medicine.

Stem cell therapy is seen as a potential new approach to the treatment of a range of chronic disease states. Stem cells injection for knee osteoarthritis oa is still a relatively new treatment and has not yet gained popularity. So the effectiveness safety and potential of mesenchymal stem cells mscs for knee oa treatment is worthy to be explored. Mesenchymal stem cells mscs are found in low numbers in normal cartilage mainly in the superficial layer acting as repairing agents.

If successful intra articular mesenchymal stem cell msc injections into the knee may offer another viable non operative treatment modality.